iTrials Site Locator™ is an evidence-based tool which pinpoints logical groupings of patients, factors investigative site requirements, and recommends site locations. An iTrials analysis first identifies potential investigators based on: clusters of eligible patients, patient densities within practices, specialties, facilities, training, board certifications, 1572 data, previous clinical trial experience, sponsor input and other variables. Weighted analysis of all investigator and facility requirements are assessed to provide recommendations for iTrials pre-qualified productive sites. Targeted investigators and sites are recruited by implementing a customized iTrials outreach and communications program to inform targeted sites about the study opportunity. This program can include further screening, pre-qualifying, and various degrees of site assessment performed by iTrials or third parties.